Pick's disease

from The American Heritage® Dictionary of the English Language, 5th Edition.

• noun A condition of progressive dementia caused by atrophy of the cerebral cortex, usually beginning in late middle age.
• noun A condition caused by constrictive pericarditis, characterized by inflammation of the peritoneum and pleura and by ascites, edema, and chronic congestion of the liver.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

• noun a progressive form of presenile dementia found most often in middle-aged and elderly women and characterized by degeneration of the frontal and temporal lobes with loss of intellectual ability and transitory aphasia